Guillain Barre Syndrome

It is an acute polyneuropathy, a disorder affecting the peripheral nervous system. 

 •Guillain barre syndromes is an autoimmune disorder of autonomic nervous system in which the patient’s body first starts shivering or pain and then after that his muscles start to weaken.

Breathing muscles weaken until symptoms are detected.
Many times the patient becomes paralyzed.  Guillain Barre syndrome (GBS) muscle weakening begins with the arms and legs(asending ).

• Symptoms of this disease take serious form within half a day to two weeks.
 •Many times it becomes so severe that the patient becomes weak to the breathing muscles and needs mechanical ventilation.  This situation can also be fatal. 

•In some patients, the function of the automatic nervous system changes.  This change causes abnormalities in the patient’s heart rate and BP, which is extremely dangerous.

Know about many important things related to Gullian Barre Syndrome:

Causes of Guillain barre syndromes :

~>Usually our immune system attacks external things, but when this system accidentally starts attacking our body functions then it is called autoimmune disease.

~> Muscle weakness disease is also an autoimmune disease of Guillain Barre syndrome, in which our body’s immune system mistakenly invades our peripheral nervous system. Because of this the myelin sheath of the peripheral nervous system is damaged or weakened.

~> When this happens, the nerves are not able to reach the signals from our body correctly from one place to another. For this reason, the ability of the muscles to react to the command of the brain, example ,the brain, begins to weaken.

~> These are the commands which are very important to capture and transport the nerve network. Not only this, our brain also gets very little sensory signals from the body due to this. As a result, the ability of the patient to feel the texture,   example:,the texture, heat, pain and other sensations of anything is affected.

 Symptoms of Guillain barre syndromes :

After this disease,
 • needle-pricking sensation in the fingers,      pain, etc.

first start appearing in the patient’s body, especially hands and feet.

 •As far as pain is concerned, more than half of the patients feel pain in the body.

•These symptoms of the disease are seen on both sides of the body equally and with time they get worse. 

• Many times, the patient also has trouble walking due to this. The neck muscle may also be affected when this disease occurs.

 •In half of the patients, the cranial nerves located in the head and face are also affected, which weakens their facial muscles and makes the face swollen.

• The muscles of the eyes also become weak. Due to this, there are problems in moving the eyes or face while talking, chewing and swallowing. Sometimes there is severe pain in the lower part of the spine.

 Other symptoms include ,

loss of control from the bladder,

rapid heartbeat,

difficulty in breathing,

paralysis ,

Symptoms of the disease start from the feet and go upwards, that is,

they first affect the hands and then the fingers.

Its symptoms increase very rapidly.  These symptoms take very severe forms within half a day to two weeks of appearance and become permanent.

 In one of five patients, this weakness of the arms and legs remains for four weeks.  

About 8 percent of people have this disease affecting the feet only. 

When the tingling of the feet or toes reaches the upper part of the body.

Toes reaches the upper part of the body.  When a tingling or weakness starts to increase rapidly, difficulty breathing or shortness of breath on your back, then see your doctor immediately.

Treatment of Guillain barre syndromes :

The doctor should be contacted immediately as soon as symptoms of this disease appear.  

Plasmapheresis is very useful treatment for Guillain barre syndromes.

What’s the purpose of plasmapheresis?

Plasmapheresis can be used to treat a variety of autoimmune disorders including:

myasthenia gravis

Guillain-Barre syndrome

chronic inflammatory demyelinating polyneuropathy

Lambert-Eaton myasthenic syndrome

It can also be used to treat certain complications of sickle cell disease, as well as certain forms of neuropathy.

 Under this, the patient’s body blood is drawn out by a machine.  When the machine removes antibodies from the blood, the extracted blood is then returned back to the patient’s body.

Plasmapheresis is a process in which the liquid part of the blood, or plasma, is separated from the blood cells. Typically, the plasma is replaced with another solution such as saline or albumin, or the plasma is treated and then returned to your body.

Physiotherapy  is very important after treatment and recovery of patients.

 Men are more affected by this disease.  About 30 percent of people in Asia and 65 percent of people in Central and South America suffer from the disease.